Todd Holland

Jeffrey Melman

Ken Kwapis

David D'Ovidio

Peter Lauer

Levie Isaacks

Steve Welch

Steve Love

Bryan Cranston

James Simons

Arlene Sanford

JamieBabbit

Jeff Melman

David Grossman

Alex Reid

Chris Koch

Nick Marck

Bob Stevens

Matthew Carlson

Christopher Masterson

Erik Per Sullivan

家里兄弟中的老四，老五出生之前的老幺，深受父母宠爱，但总被哥哥们欺负；前期以卖萌为生，幸运值爆棚，成长后情商爆表，甚至碾压以天才著称的三哥Malcolm，是个人见人爱的小鬼头。

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Craig Lamar Traylor

David Anthony Higgins

Emy Coligado

Kenneth Mars

Eric Nenninger

Gary Williams

Kristin Quick

Daniel von Bargen

Will Jennings

Drew Powell

Cloris Leachman

Arjay Smith

John Ennis

Karim Prince

Chris Eigeman

Edward James Gage

Dan Martin

Alex Morris

Jonathan Craig Williams

Merrin Dungey

Todd Giebenhain

Victor Z. Isaac

Brenda Wehle

James Rodriguez

Lukas Rodriguez

Cameron Monaghan

Tania Raymonde

Richard Gross

Brittany Renee Finamore

Derek Cox-Berg

James Henriksen

Paul Lee Willson

Hayden Leslie Panettiere

Julie Haggerty

Steve Rankin

Landry Allbritht

Javier Grajeda

Jonny Acker

Gary Ambrosia

Ivan Naranjo

Amy Bruckner

Steve Vinovich

Michael Chieffo

Vernee Watson-Johnson

Paul Gleason

Kevin Brief

Kevin Christy

Tom Virture

Beth Grant

Nancy Lenehan

Patricia Place

David Weisenberg

Michael Horse

Bart McCarthy

José Espinoza

Adam Hendershott

Parker Mills

Justin Pierce

Scott Adsit

Chase Ellison

Heather McPhaul

Randy Thompson

Joan Blair

Casey Sander

Alessandra Torresani

Christopher DerGregorian

Amy Farrington

Christopher Michael Moore

Eric Payne

Weston Blakesley

Lillian Adams

Gloria LeRoy

Fiona Hale

Dennis Cockrum

Michael Shamus Wiles

Frederick Dawson

Aaron Hill

Susan Sarandon

Caitlin Crosby

Brad Bufanda

Tom Lent

Jennette McCurdy

Larry Dorf

Jack McGee

Helen Slayton-Hughes

Christie Lynn Smith

Margie Loomis

Rodrigo Rojas

Evan Sabara

Patrick Bristow

Tricia O'Kelley

Dave Power

Wells Rosales

Nicolas Roye

Rose Abdoo

Yun Choi

Amy Davidson

Joseph Segura

Oscar Nunez

Jane Kaczmarek

Bryan Cranston

饰：Hal

Christopher Masterson

饰：Francis

家里兄弟中的老大，初代熊孩子，鸡飞狗跳惹是生非，被老妈送入了军事学校管教；大哥的终生目标似乎就是与老妈作对，凭借丰富的战斗经验经常指点弟弟们，赢得了所有弟弟的崇拜喜爱；大哥天生具有反抗精神，但随着年龄增长，渐渐成为了个可靠有爱的男子汉。

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Justin Berfield

饰：Reese

家里兄弟中的老二，头脑简单四肢发达，校园小霸王，让老妈最头疼的熊孩子；二哥性格单纯，直肠子，经常作出让人啼笑皆非的事情；另方面，乐天派的他，也常常让Malcolm羡慕，兄弟间爱恨交加；另，二哥在厨艺方面极具天赋。

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Frankie Muniz

饰：Malcolm

Scott Haven

Norma Michaels

Frankie Muniz

饰：Malcolm

兄弟中排行老三，本剧主角，智商高达165的天才少年，可打破次元壁向观众介绍背景，抒发感慨等。Malcolm智商极高，但情商捉急，尤其是人际交往方面，导致青春期感情极为坎坷；身处这个极度复杂的家庭中，经常感觉压力山大，所以爱抱怨，但本性正直善良，凭借天才的头脑常力挽狂澜，担负着家族的希望。

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Meagen Fay

Danny McCarthy

Terry Rhoads

Howie Long

Ron West

Jim Jansen

Reggie Jordan

Margarita Franco

Leslie David Baker

Clyde Kusatsu

Robert Loggia

Stuart Pankin

Stephen Tobolowsky

NickWechsler

David Cassidy

Laurie Metcalf

Caroline Aaron

：Erik King

Larisa Romanovna Oleynik

Dan Butler

Timothy Stack

Tara Karsian

Jack Axelrod

Julia Levy Boeken

Kathleen York

Tara Lipinski

Hallee Hirsh

Dewey Weber

Robin Riker

Sam McMurray

Cristine Rose

Peter Breitmayer

David Doty

Tim DeKay

Jay Johnston

Magic Johnson

Todd Stashwick

Mimi Paley

Stephanie Lemelin

McNally Sagal

Kaitlin Cullum

Julia Campbell

Art LaFleur

Anastasia Baranova

Harold Sylvester

Davenia McFadden

CeCe Tsou

Stephen Lee

Maurice Godin

Amy Halloran

James Michael McCauley

Mark Christopher Lawrence

Maz Jobrani

Kurt Fuller（Curtis Fuller）

Gregory Jbara

Heidi Klum

Timm Sharp

Marshall Allman

Robert Joy

James Black

Kevin Cooney

Justin Martin

Ellen Hollman

Alex Weed

Geoff Meed

Bruno Amato

Fred Applegate

Mimi Cozzens

Marisa Theodore

George Takei

Sandra Purpuro

Jan Hoag

Frank Crim

Joel McKinnon Miller

Alison La Placa

Aloma Wright

Lauren Hodges

Teresa Velarde

Shaun Toub

Jim O'Heir

Karen Witter

Mike Grief

Randy McPherson

Jeanine Jackson

Kat Graham

Don McManus

Ted Rooney

Kirk Ward

Mark Chaet

Henry Gibson

Matt Malloy

Andrew James Allen

Dan O'Connor

Vanessa Marano

Michael McShane

Ashley Gardner

Soren Fulton

Eva La Dare

Michael Kagan

Nolan North

Matthew Willig

Shanna Collins

Sonya Eddy

Octavia Spencer

Joel McCrary

Joan McMurtrey

Bob Clendenin

Jerry Hauck

Daniel Roebuck

Ransford Doherty

Brian Stepanek

Gregg Binkley

John O'Brien

Dale E. Turner

Michelle Durham

Sara Paxton

Jeanette Miller

Shashawnee Hall

Carlie Westerman

Kathryn Joosten

Aaron Hendry

Terence Bernie Hines

Lamont Thompson

Hayley DuMond

Rick Zieff

Johanna McKay

Michael Robert Berger

Jade Carter

Arsenio 'Sonny' Trinidad

Stan Sellers

Robert R. Shafer

Clement Blake

Melvin Dimas Rodriguez

Matt Battaglia

Steve Barr

John Valdetero

Carlo Manchini

Vic Polizos

Julian Barnes

Brett Gilbert

Derek Waters

Andy Umberger

Reggie Jackson

Tom Simmons

Deborah May

Elyse Mirto

Marty West

Alanna Masterson

Nestor Serrano

Diane Robin

Jason Dohring

Johnny K. Lewis

Sean Marquette

Jayne Taini

Nick Toth

Florence Stanley

Bette Rae

Dana Davis

Bonita Friedericy

Jean Sincere

Teddy Lane Jr.

Kotoko Kawamura

Mark L. Taylor

Michael Merton

Howard Mann

Kate Miner

Mitch Silpa

Brian Mulligan

Barton Tinapp

Steven Christopher Parker

Debbie Zipp

Bobby McGee

Dean Bates

Michaela Watkins

ZachMills

Raymond O'Connor

Andrea Silvers

Reid Collums

Andy Mackenzie

Dakota Fanning

Adam Cagley

Doug Cox

Michael Emanuel

Deborah Harmon

Bret Loehr

Tom Towles

Angela Little

Ben Livingston

Dominic Colón

David Reynolds

Brendan Walsh

Kurtwood Smith

Larry Clarke

Jill Basey

Aaron Brumfield

Kathleen Garrett

Samantha Streets

Tinsley Grimes

Marsha Clark

Laura Henry

Ashlee Simpson

Charles Emmett

Logan O'Brien

Roger W. Morrissey

Karl T. Wright

Angee Hughes

Byrne Offutt

Larry Hankin

Don Perry

Frankie J. Allison

Hayley Erin

Monti Sharp

David Trice

Matt Crabtree

Michael Krawic

Melissa Marsala

Ellis Williams

Marcella Lentz-Pope

Sheila Shaw

Theo Rossi

Christian Shannon Gann

Steven Houska

Albert Owens

Jonathan Schmock

Nasser Faris

Dan Desmond

Cody Arens

Howard George

Mike Randleman

Lorenzo James Henrie

Lorin McCraley

DeeDee Rescher

Daylon Reese

Susan Yeagley

Rick Scarry

Linda Porter

Brianna Deutsch

Billy Mayo

Teresa Ganzel

Tom McCleister

Elisa Leonetti

James Edson

James DiStefano

Robin Krieger

Eddie Pepitone

Richard Topol

Easton Gage

Stella Bach

Katherine Boecher

Fitzhugh G. Houston

Al Rondon

Sally Ann Brooks

Jon Beavers

Fernando Jiménez

Benita Krista Nall

John Colella

Vivian Smallwood

Jonathan Pickett

Asante Jones

Danny Bolero

Kevin 'Repo' Thomas

Craig Barnett

Jason Huber

Michael Q. Schmidt

Rosanna Arquette

Elizabeth Regen

Ashley Tisdale

David Ury

Jeff Bowser

Spencer Pennington

Rishonda Napier

Michael Patrick McGill

Ivan Baccarat

Bill Rutkowski

Kim Delgado

Elizabeth Payne

Titus Napoleon

Shannon Whirry

Patrick Thomas O'Brien

Micah Henson

Yolanda Snowball

David Bickford

Luis Chávez

Regi Davis

Cord Jackman

Beverly Polcyn

Larry Bagby

Wesley Thompson

Steve Tom

Jake Richardson

Vaughn Johseph

Jesse Bostick

Jesse David Corti

Thomas Lumberg Jr.

Raven Goodwin

Terry Bradshaw

Patrick Warburton

Guy Pinkham

Mildred Dumas

Rhomeyn Johnson

Trevor Shores

Steve Root

Bill Timoney

Lauren Storm

Michael Kostroff

Steve Witting

Bob Glouberman

Bea Arthur

Peter Mackenzie

Alex McKenna

Christopher Lloyd

Andy Richter

Jason Alexander

Lisa Foiles

Betty White

Michael Gaston

Michael Milhoan

Fredric Lehne

Markus Flanagan

Thomas Kopache

Jeff Doucette

Bess Meisler

Lynsey Bartilson

Perry Anzilotti

Robert Curtis-Brown

Edie McClurg

Miriam Flynn

Dave Allen

Anthony Holiday

Brenda Strong

Tom Green

Wayne Wilderson

Danielle Panabaker

David Rasche

James Hong

Adam Wylie

Travis Van Winkle

Sam Anderson

Mary Gross

Lorna Raver

Peter Siragusa

Rob Elk

Mark DeCarlo

Brian Palermo

Murray Rubin

Busy Philipps

Melody Perkins

Cerina Vincent

Jerry Trainor

Steven Gilborn

Jim Meskimen

Kevin Kilner

Holmes Osborne

Sherman Howard

Mark Moses

Michael Dempsey

Christopher Jones

Erik von Detten

John Joseph Ducey

Lilyan Chauvin

Bob Koherr

Richard V. Licata

Danielle Savre

Scott Klace

Doug Ballard

James Geralden

Alexander Gould

Natasha Melnick

Mark Tymchyshyn

Michael Alan Welch

Torsten Voges

Curtis Andersen

Lindsey Haun

Joel Murray

David Burke

John Eric Bentley

Lane Toran

Alex Boling

Joel Anderson

Lyndsy Fonseca

Patricia Belcher

Monique Coleman

Ingo Neuhaus

Lindsey Ginter

Drew Massey

Gil Glasgow

SarahFayWright

Leah Pipes

Sam Lloyd

Wes Robinson

Blaire Baron

Emma Stone

Yvette Nicole Brown

Stuart Fratkin

Martin Spanjers

Marc Vann

Colin Ferguson

Garret Davis

Christina Ricci

Bradley Whitford

Tom Tartamella

Ursula Whittaker

Kyle Searles

Jackie Harris

Michelle Anne Johnson

Jamie Renée Smith

Ryan Malgarini

Kristina Hayes

Carolyn Seymour

Carla Jimenez

Jonathan Hernandez

Kevin Michael Richardson

RoarkGrantCritchlow （本名）

Jeff Braine

Jerry Lambert

Frank Clem

Robert Briscoe Evans

Robert Grovich

Todd Eckert

Mary Pat Gleason

E.J. Callahan

Sharon Omi

George Wyner

Michael Bailey Smith

Trieu Tran

Jeremy Roberts

Matt Corboy

Michael Dean Jacobs

Darlene Kardon

Eddie Shin

Regan Burns

Judith Moreland

John DiResta

Cindy Lu

Andrew Reville

Larry Marko

Kevin Thompson

Atticus Todd

Don Pugsley

Perry D'Marco

Kate Micucci

Paul Rae

Eric Stonestreet

John Lacy